Vibrant’s Micronutrient test is the only test that provides a comprehensive extracellular and intracellular assessment of the levels of the most important vitamins, minerals, antioxidants, fatty acids, and amino acids. Knowing both your extracellular and intracellular micronutrient levels are key to a thorough understanding of your nutritional requirements at a foundational level, which may contribute to your risk for disease, while simultaneously and positively impacting your overall health and well-being.

EXTRACELLULAR MICRONUTRIENTS

Extracellular Micronutrients that are free-floating in your blood and exist outside the cells, determined in serum are called extracellular micronutrients.

These extracellular micronutrients are a static measure of what is in your blood at any given time. These are dependent on your short-term intake of supplements or diet and give a direct assessment of your baseline micronutrient levels.

Extracellular nutrient tests reflect a person’s diet over a relatively narrow time frame.

INTRACELLULAR MICRONUTRIENTS

Intracellular micronutrients are the micronutrients absorbed by your circulating white blood cells and red blood cells. Cellular micronutrient absorption is an important step in maintaining and promoting optimal functioning of all our cells.

It is important to understand that, even though you may be consuming an adequate or healthy diet or supplements, your cellular intake levels of those nutrients may not be sufficient and may still provide risks for deficiencies and the disorders associated with them.

Your genetics, aging, lifestyle, chronic illness, and medications all affect your cellular nutrient absorption. The intracellular portion of Vibrant’s micronutrient test takes all the above factors into consideration to identify your cellular nutrient absorption status. This test can reveal a person’s functional nutritional status over a much longer time (4-6 months) than extracellular testing.

VITAMINS

MINERALS

AMINO ACIDS

ANTIOXIDANTS

METABOLITES

INTRACELLULAR RBC

Role of Micronutrients

Almost every physiological function in your body requires micronutrients to function optimally. Vitamin, minerals and anti-oxidants play a key role in:

Who Should Be Tested?

This testing would be most beneficial if you:

A. Suffer From

B. Are Experiencing

C. Have a History of

D. Are Someone who is a

This test is designed to distinguish between celiac disease, non-celiac gluten sensitivity, non- gluten wheat sensitivity, and other autoimmune diseases triggered by gluten. It also includes the market’s most comprehensive biomarker panel to identify intestinal permeability (leaky gut syndrome). The Wheat Zoomer has been validated at 99% specificity and sensitivity.

What is wheat/gluten sensitivity?

Wheat and gluten sensitivities are immune responses in which, upon ingestion of wheat or gluten (from gluten-containing grains), antibodies against the protein component of these grains are generated. Gluten sensitivity is only a subset of a much larger group of wheat/gluten-related disorders.

Symptoms and conditions associated with wheat/gluten sensitivity:

The Wheat Zoomer allows detection of protein antibodies associated with wheat and gluten sensitivities for information to reduce, monitor and manage the inflammatory effects of those sensitivities.

Wheat Zoomer Intestinal Antibody Detection Includes:

Wheat Zoomer Intestinal Permeability Panel includes:

GUT BACTERIA, PARASITES, FUNGI, AND VIRUS

This test provides an unique opportunity to better understand your gut microbiome. This is a microchip-based exploration service that allows you to look at the populations of bacteria that reside in your gut. This test is based on extensive research from the NIH Human Microbiome project. The Gut Zoomer looks at specific DNA fragments that identify the unique bacteria in your sample. 16S Ribosomal Gene enables us to classify and distinguish bacteria from phylum up to sub-species level.

WHAT IS THE GUT MICROBIOME?

The gut microbiome, which hosts more than 1000 bacterial species that encode about 5 million genes, performs many of the important functions like aid in the digestion of foods, immune system development, vitamin synthesis, ion absorption, salvage of energy, which our body cannot perform by itself. As its name states, gut microbiome is harbored in the intestine, one of the main areas in our bodies that comes into contact with the external environment (other examples are the skin and the lungs). Alterations in the composition of the gut microbiome could lead to a bacterial imbalance which has been related to an increasing number of intestinal and extra-intestinal diseases. Some of the factors that lead to such imbalances include:

GUT MICROBIOME IMBALANCE EFFECTS

Imbalances in your gut microbiome may lead to the following symptoms/effects:

GUT MICROBIOME IMBALANCE TESTING

Of all the bacterial species, only about a 100 types have potential health outcomes based on existing scientific studies and peer-reviewed journals.

It is important to know the abundance of these bacteria to make healthy lifestyle decisions. Some of these include:

BACTERIA

PATHOGENIC BACTERIA

BACTERIA

The Gut Zoomer performs the most comprehensive analysis available of your microbial profile from a simple and easy to use feces collection kit and provides you with an actionable report that includes potential risks for:

Food Sensitivity is your body’s response (IgG antibody reactions) to certain foods that occur hours to days after certain foods are consumed. These are also termed as delayed food reactions.

This test uses a chemiluminescent method of detecting food sensitivities on a silicon chip. This proprietary technology allows for the highest sensitivity of detection. Vibrant tests for IgG and IgA antibodies to food. These are delayed sensitivities which can take up to 72 hours to appear.

This test identifies both IgG and IgA reactivity to 96 of the most commonly consumed foods including dairy, meat, seafood, fruits, vegetables, grains, legumes, nuts, nightshades, and more.

SYMPTOMS TO CONSIDER FOOD SENSITIVITY TESTING

Undetected food sensitivities could lead to symptoms and systemic changes that are associated with certain conditions/illness:

DIGESTIVE DISORDERS

Conditions like irritable bowel syndrome (IBS) and Crohn’s disease have been linked to IgG food reactions. Research has shown that elimination of IgG reactive foods can alleviate IBS symptoms.

MIGRAINES

A 2007 research study found that 43/65 patients with migraine headaches had complete remission of headaches after one month of eliminating reactive foods. Another study in 2010 found a significant reduction in the number of headache days and migraine attacks with elimination of reactive foods.

MOOD/ATTENTION DEFICIT DISORDERS

Deposition of antibody-antigen complexes in nervous system tissues may contribute to hyperactivity, depression, anxiety, inability to concentrate and other mood disorders. There is some evidence that eliminating IgG food antigens improve attentiveness in children.

WEIGHT GAIN

Antibody-antigen complexes in tissue cause inflammation, which leads to fluid retention and weight gain. To fight inflammation, the body releases a chemical called ghrelin, which also happens to be an appetite stimulant. Thus, IgG food reactions may contribute to weight gain in two ways: fluid retention and increased appetite.

WHY TEST FOR FOOD SENSITIVITIES?

Since food sensitivities are delayed reactions, testing is the only way to determine which foods are responsible for the reaction. IgG reactions frequently occur to commonly consumed foods such as dairy, wheat, eggs, yeast, pork and soy.

(removing suspect foods for a period of time and then reintroduce and check for reactions) are difficult to follow and can take months to complete.

Can be implemented working with our team of clinical dietitians.

HOW DOES DUTCH COMPARE TO OTHER HORMONE TESTS?

This advanced hormone testing was developed to improve on available hormone testing options. DUTCH offers the most extensive profile of sex and adrenal hormones along with their metabolites. Additionally, the daily (diurnal) pattern of free cortisol is included, along with melatonin (6-OHMS), 8-OHdG, and six organic acids. This unique combination of clinical information is not available by any other method.

DUTCH COMPLETE

DUTCH PLUS

DUTCH CYCLE MAPPING (FEMALE ONLY)

DUTCH CYCLE MAPPING & COMPLETE BUNDLE (FEMALE ONLY)

CORTISOL AWAKENING RESPONSE

DUTCH SEX HORMONE METABOLITES

DUTCH ADRENAL

DUTCH VS. SALIVA TESTING

While the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.

DUTCH VS. SERUM TESTING

While the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).

DUTCH VS. 24-HOUR URINE TESTING

There are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.

WHAT CAN THE DUTCH PLUS™TELL US THAT THE DUTCH COMPLETE CANNOT?

Even though a patient may have “normal” free cortisol levels throughout the day, that doesn’t always mean everything is functioning properly. The graph below shows two good examples. A blunted or exaggerated Cortisol Awakening Response (CAR) can appear, even when single samples return “normal” results. The HPA axis might not be appropriately responding when faced with a stressor, even when cortisol levels are fluctuating nicely throughout the day. The “stress” of waking allows us to test the HPA axis in a way that has been independently correlated to clinical outcomes and cannot be assessed by other cortisol tests on the market.

DUTCH Sample Report for Men

DUTCH Sample Report for Women

Hormones

Micronutrients

Vitamins

Antioxidants

Amino Acids

Electrolytes

Metabolites

Minerals

Omega Fatty Acids